Biotech jobs in United Kingdom

About Oxford Biotherapeutics

Oxford Biotherapeutics is a clinical-stage biotechnology company specializing in the development of antibody therapeutics for the treatment of cancers. You will play an integral role in the discovery of new antibody-based oncology therapeutics. Our OGAP verify platform is the world's largest, cancer specific, membrane protein library, directly measuring plasma membrane protein expression in patient tumors. OGAP verify is used to identify novel, highly tumor specific antigens for novel first-in-class Antibody Drug Conjugates (ADC), T-cell Engagers (TCE) and Chimeric Antigen Receptor T Cell (CAR-T) therapeutic targets. Our lead asset, OBT076, is an Antibody Drug Conjugate in Phase 1b clinical development. Our clinical and pre-clinical pipeline of novel biologics is balanced between internal programs, focused on ADCs and checkpoint regulators, and externally partnered programs with key innovators in oncology such as Roche and Boehringer Ingelheim.

Purpose of the Role

To perform laboratory-based research in collaboration with others with the aim of identifying new therapeutic cancer targets. The laboratory techniques may include proteomics, mass spectrometry, human tissue analysis, liquid chromatography, protein quantitation and data analysis. You will be required to adhere to regulatory standards, particularly the treatment of human tissues, and assist with general lab duties. Training will be provided where required.

Roles and Responsibilities:

• This is a laboratory-based role.
• Diligent, careful and reproduce by following Standard-Operating Procedures.
• Duties may include processing of human tissues using biochemical methods.
• Operation of mass spectrometers and associated chromatography systems.
• Ensuring compliance with relevant health and safety regulations.
• Ensuring compliance with regulations on handling of human tissues under the Human Tissue Act.
• Prioritise work according to project goals and take responsibility for the timely delivery of individual and team objectives.
• Culturing of cell line.
• Contributing to general lab duties (e.g., maintenance, stocking, cleaning).
• Record and analyse data.
• Perform routine data analysis using proteomics software tools (30% time of one of the roles).

Please note the roles and responsibilities for the position include but are not limited to the above.

Knowledge, Experience, and Skills:

• Must have a minimum BSc in Biology or biochemical or chemistry related field with demonstrable laboratory experience. An MSc in Biology, Chemistry or biochemistry related discipline is preferred.
• Additional laboratory experience would be advantageous.
• Previous experience with mammalian cell culture or working with human tissues is desirable.
• Ability to follow Standard Operating Procedures (SoPs).
• Confident working in a laboratory environment.
• Ability to maintain accurate records (e.g., maintenance of databases and Electronic Lab Notebooks (ELNs)).
• A Preference for candidates who are already vaccinated against Hepatitis B. If not, candidate must be willing to be vaccinated to work with human tissues.
• Be prepared to work with human tissue samples.
• Skilled in using Microsoft Office packages.
• Previous experience with proteomics, mass spectrometers or HPLCs is desirable but not required.
• Attention to detail when performing repetitive tasks.
• Excellent ability to relay complex scientific information to different audiences.
• Ability to work with minimal supervision and maintain a high standard of confidentiality.
• Confident engaging with colleagues.
• Ability to work in a matrix reporting structure.

Behaviours

• Team player
• A positive attitude
• Enthusiasm
• Self-motivated
• A flexible and agile approach
• Attention to detail
• Ability to prioritise different work requirements
• Ability to follow instructions
• Careful and methodical approach
• Ability to perform repetitive tasks in a reproducible manner
• Enjoys laboratory-based work

Benefits Offered:

• Private health care (Bupa)
• Health Cash Plan
• Generous pension scheme with potential employer contribution of up to 10% (based on match contributions)
• Discretionary Annual bonus scheme
• Free onsite parking
• Office snacks
• Enhanced holiday entitlement above statutory minimum plus public holidays
• Employee Referral Bonus Program
• Annual training budget for professional development
• New hire stock options
• Team building events and activities

Pay Range: 26-30K GBP Per annum.

Equal Opportunities Statement

OBT is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status, and veteran status. All qualified applicants will receive consideration for employment.

Why Join Us - We promote a culture of innovation, responsibility, and commitment to our goals and objectives. Together, we believe, we can pool our resources and our uniqueness to develop novel, robust cures for one of the most challenging health conditions today. We recognize that our team is only as good as the people in it. Our people have used the words friendly, collaborative, and hard working to describe the culture here at OBT. This is why, while we strive to ensure that we hire only the best people, we also strive to provide a working environment that is based on cooperation, innovation, and mutual respect.