Biomedical Scientist jobs in United Arab Emirates

Organisation/Company: KINGS COLLEGE LONDON

Research Field: Biological sciences

Researcher Profile: Recognised Researcher (R2), Established Researcher (R3)

Country: United Kingdom

Application Deadline: 8 Apr 2025 - 00:00 (UTC)

Type of Contract: Other

Job Status: Full-time

Is the job funded through the EU Research Framework Programme? Not funded by a EU programme

Is the Job related to staff position within a Research Infrastructure? No

About Us

The KCL School of Immunology & Microbial Sciences and its Department of Infectious Diseases are internationally recognised for the broad spectrum of approaches they use to understand infectious diseases and improve health and well-being. The School and Department host world leaders in immunology, pathogen molecular biology and host-pathogen interactions, encompassing a wealth of knowledge, expertise, and experience.

We are seeking a candidate that has obtained (or will obtain soon) a PhD in a relevant subject (i.e. virology, immunology, microbiology, molecular biology, cell biology). Experience working with pathogens (ideally viruses) and/or innate immunity is essential. The lab uses a combination of molecular techniques (e.g. transcriptomics, proteomics, luciferase-based reporter assays, immunoblotting, RT-qPCR, microscopy, generation of recombinant viruses) to study innate immunity in the context of viral infection. Prior experience in some of these techniques is desirable.

Our current research programme aims to address three main themes/questions, using viruses with a DNA component to their life cycle (poxviruses, including mpox, herpesviruses, lentiviruses) as tools for discovery:

1. How are viruses sensed by host cells (particularly by DNA sensors such as cGAS) and how do viruses evade detection and innate immune activation?
2. Which innate immune proteins act as barriers to infection, particularly against zoonotic viruses, and how do viruses overcome them?
3. How is innate sensing regulated during homeostasis (e.g. during cell division) and subsequently dysregulated during viral infection/in diseases states such as cancer?

This is a full-time post (35 hours per week) and you will be offered a fixed term contract for 24 months.

To be successful in this role, we are looking for candidates to have the following skills and experience:

• PhD in a relevant subject area (i.e. virology, immunology, microbiology, molecular biology, cell biology)
• Track record of publication or clear potential for publication in leading biomedical journals
• Extensive experience in major molecular biology, biochemistry and cell biology techniques
• Experience working with pathogens (ideally viruses) and/or innate immunity
• Excellent written and presentational skills
• Ability to work collegially within a team and with external collaborators
• Ability to independently design, implement and analyse experiments

* Please note that this is a PhD level role but candidates who have submitted their thesis and are awaiting award of their PhDs will be considered. In these circumstances the appointment will be made at Grade 5, spine point 30 with the title of Research Assistant. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6.

• Experience in handling and the molecular manipulation of DNA viruses, particularly HCMV
• Experience with RNAi and/or CRISPR mutagenesis
• Experience with ‘omics techniques, including transcriptomics and proteomics, and analysis of the generated datasets

Grade and Salary: £44,355 per annum, including London Weighting Allowance

Job ID: 108805

Close Date: 08-Apr-2025

Contact Person: Dr Rebecca Sumner

Contact Details: rebecca.sumner@kcl.ac.uk