Senior Bioinformatician

Immunocore; Oxford; On-site; GBP 40,000 - 80,000

Job description

Key Responsibilities To provide focused bioinformatics expertise to support the analysis and data management of translational biomarker data. This individual will be expected to thoroughly explore publicly available data together with emerging data from Immunocore’s clinical trials to provide new insights into mechanism of action, molecular heterogeneity of disease and novel targets.

KEY RESPONSIBILITIES

1. Conduct the analysis of transcriptomic and genomic sequencing data from our clinical trials.
2. Compliment and develop our scientific hypotheses through the mining of public data and the design and analysis of our own in-house experiments.
3. Develop custom-made tools and analytics to assist interpretation and data visualisation.
4. Contribute to abstracts and manuscripts as required.
5. Maintain and increase technical knowledge in relevant fields through self-study, observation, attending relevant conferences and training courses.
6. Maintain accurate records of all work by completing documentation on time, following Company procedures.
7. Operate in accordance with the Company’s Health and Safety policies.

SPECIFIC RESPONSIBILITIES

1. Data analysis: independently testing and, increasingly, leading lines of investigation. Proposing new analyses based on emerging data and other related information. Providing support on technical aspects to others.
2. Priorities: establishing priorities for own work and team-based projects; making decisions on prioritisation based on the overall goals of the team, department and project, using direct evidence and personal experience as guidance.
3. Technical Knowledge: sharing knowledge with the wider team and, across departments representing the department both internally and externally. May also act as a mentor or manager to other colleagues, especially new hires, sharing scientific and company knowledge.
4. Record keeping: ensuring that all records and information are up to date, on time and recorded to the correct standard. Supporting and encouraging others to achieve this.
5. Equipment: providing technical guidance to others within the team on how to use equipment most effectively; making recommendations regarding acquisition of new pieces of equipment.
6. Health & Safety: championing and helping others to understand H&S within the company, providing ad-hoc training as required.
7. Reporting: communicating and presenting research findings at meetings with colleagues, senior management and partners.

PERSON SPECIFICATION

EXPERIENCE AND KNOWLEDGE

Essential

1. Proficient in R/BioConductor, Linux OS and shell scripting bash. Proven programming ability (Knowledge of at least one language, preferably Python).
2. Understanding of molecular biology, cell biology, immunology or related discipline.
3. Significant experience of independent research in academic or industrial setting, or transferable skills gained from professional experience.
4. Proposed and driven changes in working practices that have improved efficiency, supported teams through adoption and change.
5. Presented detailed scientific findings and papers to internal and external audiences.
6. Recorded results in a concise and timely way, and in compliance with agreed standards.
7. Experience of building next generation sequencing (NGS) analytical pipelines.

Desirable

1. Led a project small team, formally or informally, including project management.
2. May have experience of developing databases, using SQL or similar, and pairing with a user-friendly interface.
3. Mentored and coached less experienced colleagues in scientific practices and theory.
4. May have knowledge of machine learning, applied statistics or related field.

EDUCATION & QUALIFICATIONS

1. PhD in a scientific discipline with a minimum of 2-5 years of relevant experience (post-doctoral experience may be included) - preferred.
2. MSc degree or BSc degree with equivalent research or industrial experience specific to the role - required.

About the Company

Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.

Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.

At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients’ lives, advancing medicine, and supporting one another in these pursuits.

Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.