Senior Computational Biologist (m/f/d), for single-cell data analysis

Senior Computational Biologist (m/f/d), for single-cell data analysis

Apply locations Germany - Berlin time type Full time posted on Posted Yesterday job requisition id 4924981

A career at Pfizer offers opportunity, ownership and impact.

All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives.

About the role:

Pfizer's cross-functional 'omics ecosystem team is actively seeking a highly motivated, creative, and seasoned senior computational biology researcher with a strong background in single-cell (+ related modalities) data analysis/integration, exceptional full-stack software engineering skills, and exemplary data handling capabilities. The ideal candidate will have an esteemed scientific reputation in the field of bioinformatics research and will play a pivotal role in our dynamic and pioneering cross-functional team dedicated to advancing the development of a cutting-edge single-cell platform for Pfizer R&D. In this role, the candidate will leverage their expertise to design innovative approaches that extract valuable insights from Pfizer's proprietary data and external datasets, enabling the generation of testable hypotheses across the entire drug discovery value chain.

Your responsibilities include:

• Development and implementation of a single-cell platform to enable efficient and scalable analysis of single-cell data and related modalities
• Development of effective machine learning data loaders together with the machine learning team for cutting-edge single cell machine learning
• Processing and analysis of internal single-cell sequencing datasets
• Curation and integration of relevant datasets from the public domain
• Development of a data dissemination concept for single-cell sequencing data and related modalities
• Implementation of new methods for single-cell data analysis and visualization
• Drive collaborations with external companies
• Develop Pfizer single-cell data strategy together with other functions from the research units
• Strengthen external visibility and scientific excellence through publishing/presenting work in reputed journals and conference/workshop venues and engaging with the scientific community

About you:

• Formal training in Computational Biology, Biology, Physics, Statistics, or related technical discipline
• PhD and several years of relevant research experience in developing single cell analysis and data integration solutions and a sincere interest in computational life sciences
• Highly creative person with outstanding problem-solving skills to tackle complex analysis tasks in a timely fashion
• Strong full-stack developer with focus on Python, in-depth database expertise with a focus on Postgres, ETL frameworks. Exceptional programming skills in Python are a prerequisite. Familiarity with pertinent libraries within the Python scientific stack would be highly advantageous
• Proficiency in utilizing AI/ML libraries including PyTorch and Lightning is essential
• Proven expertise in software engineering, package development, cloud architectures, CI/CD, and software engineering tooling
• Hands-on experience in handling, processing, integrating, and analyzing large heterogeneous data sets related to single-cell sequencing data in a drug discovery research environment
• Strong publication record and demonstrated contributions to the field
• Passion and curiosity for data and proven ability to take ideas from prototype to production
• Strong interpersonal skills, distinct collaborative attitude, excellent written and verbal communication

Together we stand for:

Breakthroughs that change patients' lives – In order to fulfill our corporate purpose, a value-oriented corporate culture guides our actions. Pfizer's values are: Courage, Excellence, Equity & Joy.

For us, it goes without saying that we offer fair remuneration in accordance with the IG BCE framework collective agreement, as well as a pension scheme and many other attractive benefits.