Postdoctoral Scientist in Ulm

The position is open immediately in the research group for neurogenomics and translational myology of Prof. Dr. Sebahattin Cirak, who is Section Head of Pediatric Neurology and Metabolics at University Ulm, searching immediately for a

Postdoctoral Scientist

The research laboratory is located within the large pediatric research center of the Department of Pediatrics and Adolescent Medicine (Director: Prof. Dr. M. Erlacher).

Your project:

Investigating cellular and molecular mechanisms of pediatric neurogenetic disorders and muscular dystrophies, mainly based on novel genomics approaches using patient samples and in-vitro models.

Your responsibilities will include:

• Discovery of novel muscular dystrophy-associated genes and molecular mechanisms by the latest state-of-the-art OMICs techniques, in particular long-read RNA sequencing and spatial transcriptomics.
• Characterization of mouse models to investigate the underlying pathophysiological mechanisms leading to muscular dystrophy.
• Development of novel antisense oligonucleotides for exon skipping therapy of Duchenne Muscular Dystrophy in-vitro and mdx mice models.
• Development of protein quantification techniques including mass spectrometry.
• Working in collaboration with an international team under supervision and leadership of the PI.
• Publishing impactful original research papers.

Our offer:

Your salary will be based on qualifications and experience, including benefits according to TV-L E13. The job is currently for around 1 year but will be extended if the candidate is successful. A very good scientific environment, a broad repertoire of methods, supportive supervision, and a friendly group. Short-term visits to other labs in Germany and abroad.

The Board of Directors of the University Hospital Ulm places strong emphasis on gender equality and seeks to increase the proportional representation of women in this field. Thus, applications from female scientists are welcome; suitably qualified women will be given preferential consideration unless other candidates clearly demonstrate superior qualifications.

We also welcome applications from disabled candidates, who will also be given preferential consideration over other applicants with comparable qualifications.

Minimum Requirements:

• Ph.D. in biology or a related field and a strong interest in drug development in genetically inherited diseases.
• Hands-on experience with animal models is desirable.
• A solid background in molecular biology is desirable.
• Ability to work on multiple projects in collaboration with others.
• Candidates with programming skills will be preferred.
• Candidates should be creative and capable of developing a competitive research project while working autonomously under the supervision of a team leader.