Senior Scientist (In Vivo Imaging Biomarkers), Biomarkers & Data Analytics, Quantitative Biosciences

Job Description

At our company, we are committed to becoming the premier, research-intensive biopharmaceutical company and are dedicated to providing leading innovations and solutions for today and the future.

Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities and robust scientific methodology we collaborate to discover the next medical breakthrough.

We are seeking a Senior Scientist to join our Biomarkers & Data Analytics team at our research laboratory in Singapore. Our team focuses on synergizing medical and disease biology, imaging & omics technology, big data, and data science to discover, develop, and deploy novel biomarkers for diseases with critical unmet needs, and to accelerate the discovery and development of new drugs.

As a Senior Scientist, you will be responsible for both independent and collaborative work within a team setting to develop advanced AI-ML-based medical imaging analytics using large biobank datasets and clinical data. This work will support the deployment and validation of imaging biomarkers for cardiometabolic and neurological diseases. You will collaborate closely with colleagues, key stakeholders, and external research institutes and CROs to build, evaluate, and qualify image analytics tools for generating impactful data-driven insights and translatable biomarkers to enable decision-making in drug development programs. Additionally, you will have the opportunity to learn from industry experts, gain exposure to a research-driven enterprise, and utilize your passion, creativity, knowledge, and collaboration skills to find solutions to challenging problems.

WHAT YOU WILL DO:

Responsibilities include, but are not limited to:

• Design, develop and validate innovative AI-enabled medical image analytics pipelines to support the deployment of imaging biomarkers for drug discovery and development.
• Generate key biomarker data driven insights through the development and deployment of novel AI-ML based analytical pipelines that enable efficient data mining of big biobank datasets.
• Design and implement innovative computational models for deriving parametric maps from medical images. Perform rigorous validation of the biomarkers with various test cases.
• Collaborate with internal and external stakeholders to design and execute imaging experiments and plans.
• Participate in team meetings and contribute to discussions on project progress and findings. Attend and potentially present at relevant conferences, demonstrating a commitment to professional growth and knowledge expansion.
• Present research results to clinical and discovery teams, including writing manuscripts for submission to peer-reviewed journals.
• Recommend changes in the direction or emphasis of original research approaches. Original ideas and concepts, creative thinking, and their implementation are expected at this level.
• Proactively suggest new research ideas, show creative thinking, and propose changes to research approaches as needed.
• Maintain data integrity and compliance by managing the data lifecycle, accurate record-keeping, and authoring documentation including image analysis workflows (e.g., SOP, QA/QC plan), research reports, project meeting minutes, and study logs.

WHAT YOU MUST HAVE:

To be successful in this role, you will have:

• PhD or Master’s degree with a minimum of 3 years of research experience in Engineering, Computational Sciences, or Biomedical/Life Sciences, with a focus on research in medical image analysis.
• Hands-on research experience in implementing AI-based medical image analysis pipeline using languages like MATLAB, Python, or R; including scikit-learn, pytorch, tensorflow tools is required.
• Hands-on research experience involving large scale imaging datasets (e.g., MRI, CT etc.) from Biobanks (e.g., UK Biobank) or cohort studies is highly advantageous.
• Proficiency in data analytics, visualization and interpretation using Python (seaborn, matplotlib) or R (ggplot2, corrplot) is required.
• Experience as a software engineer in software development, specifically in medical image processing, and as a full stack developer with proficiency in Python, Java, and JavaScript would be advantageous.
• Knowledge in cardiometabolic disease and/or neuroscience disease biology is highly desired.
• Strong organizational skills, attention to detail, and ability to work independently and as part of a team.
• Ability to prioritize multiple tasks and strong time management skills to meet challenging study timelines.
• Ability to learn drug research and disease biology and develop appropriate imaging biomarker solutions to overcome challenges associated with drug discovery and development.
• Strong written and oral communication skills.
• Self-inspired and enthusiastic team player capable of working in a highly collaborative, cross-functional working environment.
• An individual who possesses a positive, proactive attitude and embodies a growth mindset.

WHAT YOU CAN EXPECT:

• Opportunity to work at the interface of multiple disciplines and integrate medical and disease biology, imaging and novel technologies, big data/biobanks and AI-ML/data science.
• Collaboration with a team committed to leveraging AI/ML for drug development.
• Opportunities for applying your innovative mindset to experiment with new ideas and approaches.
• A supportive working environment that fosters career growth and continuous learning.

Additional Information:

• Please provide a LinkedIn profile, publications in conferences/journals, or any relevant profiles (Google Scholar, Github, Stack Overflow, Arxiv, and/or Kaggle) if available.

WHO WE ARE …

We are known as Merck & Co., Inc., Rahway, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” and that great medicines can make a significant impact to our world. And we believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

WHAT WE LOOK FOR …

Imagine getting up in the morning for a job as important as helping to save and improve lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a diverse group of colleagues who pursue and bring hope to countless people who are battling some of the most challenging diseases of our time. Our team is constantly evolving, so if you are among the intellectually curious, join us — and start making your impact today.

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

Current Employees apply HERE

Current Contingent Workers apply HERE

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status: Temporary (Fixed Term)

Relocation:

VISA Sponsorship:

Travel Requirements:

Flexible Work Arrangements: Hybrid

Shift:

Valid Driving License:

Hazardous Material(s):

Required Skills: Business Intelligence (BI), Database Design, Data Engineering, Data Modeling, Data Science, Data Visualization, Machine Learning, Software Development, Stakeholder Relationship Management, Waterfall Project Management

Preferred Skills:

Job Posting End Date: 12/26/2024

*A job posting is effective until 11:59:59PM on the day BEFOREthe listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID: R314821