Impact of biological ageing and the cellular senescence in the pathophysiology of periodontitis

Organisation/Company: Università degli Studi di Torino

Research Field: Medical sciences

Researcher Profile: Recognised Researcher (R2), Leading Researcher (R4), First Stage Researcher (R1), Established Researcher (R3)

Country: Italy

Application Deadline: 27 Jan 2025 - 13:00 (UTC)

Type of Contract: To be defined

Job Status: Not Applicable

Is the job funded through the EU Research Framework Programme? Not funded by a EU programme

Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Bioscaffolds fabricated through 3D printing will be utilized to investigate tissue engineering solutions tailored for aged and senescent environments. Additionally, transcriptomic and proteomic analyses will elucidate the molecular interactions between senescent cells, inflammatory mediators, and MSC functionality in the periodontal niche. The project also aims to evaluate the efficacy of innovative regenerative techniques, such as scaffold-based periodontal tissue reconstruction, in restoring lost structures and functionality. By combining insights from cellular biology, tissue engineering, and clinical reconstruction, this project aspires to deliver novel therapeutic strategies that address the challenges of periodontitis in aging populations.

Eligibility of Fellows

Country/ies of residence: All

Nationality/ies: