Senior Research Scientist, Bioanalytical

Waters Corporation; Cambridge; On-site; GBP 80,000 - 100,000; Full time

Job description

Overview

Waters Global Research is looking for an energetic and creative scientist to join the research team at our Cambridge, MA lab to elevate PROTAC and molecular glues characterization and analysis. This unique position sits at the intersection of Biology, Chemistry, and Analytical sciences and will require close collaboration with an industrial partner. The Global Research team is looking for an enthusiastic early career individual with experience in immunoassays, LC-MS, and protein chemistry to contribute to innovations in the analysis of next-generation therapeutics. The ideal candidate will help change how we think about problems, inspire new ideas, and challenge conventional approaches in bioanalytical chemistry.

The Waters Global Research team performs early, cutting-edge research on novel separation technologies and automation systems used in measurements of the life, food, and materials sciences industries. We are committed to understanding customer needs and pivoting these insights into new and exciting technologies to address those needs. Global Research is a cross-functional research team focused on step-change innovations in the Liquid Chromatography, Mass Spectrometry, Biologics, Clinical, Chemistry, and Informatics products and is dedicated to exploring technologies and developing novel system solutions for the critical problems of the life sciences. Waters is dedicated to solving problems that matter, achieving greater sustainability, and fostering a culture of inclusion and equity.

Responsibilities

1. Conduct research activities for customer problems within the Global Research Team using state-of-the-art chromatography and mass spectrometry instrumentation; utilize affinity technologies in protein profiling, cell and gene therapy, Molecular glues, PROTAC, and ubiquitin characterization.
2. Conduct systematic test measurements with prototypes and available instrumentation.
3. Prepare detailed technical reports, draw conclusions based on strong data analysis, contribute to patent applications, and provide internal and external presentations to summarize scientific findings.
4. Provide technical support, share development ideas, contribute to our global research portfolio, and assist in effective research planning.
5. Provide technical support to external collaborators where applicable.
6. Stay up to date in scientific literature for specific areas of specialization.
7. Establish procedures and work effectively with cross-functional project teams, including scientists, biologists, chemists, and engineers.

Qualifications

Qualifications

1. Ph.D. in Biochemistry, Biology, Chemistry, or related discipline.
2. MS in Chemistry, Biology, Engineering, or related field with 3+ years of relevant experience.
3. MS with 6+ years of relevant experience.

Key Experience

1. Hands-on experience with column technologies, separation science, sample preparation, and high resolution mass spectrometry.
2. Bottom-up or top-down proteomics experience is preferred.
3. Basic understanding of protein/peptide analysis, immunoprecipitation sample prep, and immunoassays (ELISA, Western Blot, etc.).
4. Experience with PROTACS, molecular glues, ubiquitin assays, or ternary protein complexes desirable.

Desired Skills

1. Innovative mindset and adaptability to diverse ideas.
2. Ability to work independently.
3. Strong communication, analytical, and decision-making skills.
4. Proficient in oral and written English communication.
5. Interest in bioanalytical data analysis.
6. Broad knowledge of bioanalytical techniques.

We know that sometimes the perfect candidate does not exist, and that people can be put off applying for a job if they do not fit all the requirements. If you are excited about working for us and have most of the skills or experience we are looking for, please go ahead and apply. You could be just what we need! We believe strongly in the value of diversity and creating supportive, inclusive environments where our colleagues can succeed. As such, Waters is proud to be an Equal Opportunity Employer and is committed to maintaining a diverse and inclusive work environment.

Company Description

Waters Corporation (NYSE: WAT), the world's leading specialty measurement company, has pioneered chromatography, mass spectrometry and thermal analysis innovations serving the life, materials, and food sciences for over 60 years. With approximately 8,000 employees worldwide, Waters operates directly in 35 countries, including 15 manufacturing facilities, with products available in more than 100 countries. Our team focuses on creating business advantages for laboratory-dependent organizations to enable significant advancement in healthcare delivery, environmental management, food safety, and water quality.

Working at Waters enables our employees to unlock the potential of their careers. Our global team is driven by purpose. We strive to be better, learn and improve every day in everything we do. We’re the problem solvers and innovators that aren’t afraid to take risks to transform the world of human health and well-being. We’re all in it together delivering benefit as one to provide the insights needed today in order to solve the challenges of tomorrow.

Diversity and inclusion are fundamental to our core values at Waters Corporation. It is our responsibility to actively implement programs and practices to drive inclusive behavior and increase diversity across the organization. We are united by diversity and thrive on it for the benefit of our employees, our products, our customers and our community. Waters is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, religion, sex, national origin, sexual orientation, age, marital status, disability, gender identity or protected Veteran status.

Key Words

Senior research scientist, PROTACS, molecular glues, ubiquitin assays, mass spectrometry #LI-HH1