Senior Laboratory Research Scientist

Location: The Francis Crick Institute, Midland Road, London

Short summary

We are seeking an enthusiastic and ambitious Senior Laboratory Research Scientist to join the Tissue Regeneration and Clonal Evolution (TRCE) laboratory. We are a multi-disciplinary research group with a mission to understand the factors underlying an organ’s regenerative capacity in order to design novel therapeutics to augment biological function.

This is a shared role between the Tissue Regeneration and Clonal Evolution (TRCE) laboratory, led by Dr. Foad Rouhani, and the Human Biology Facility (HBF), led by Dr. Jennifer Hay. The major component of the role involves carrying out a substantial research project in the TRCE lab focused on applying cutting-edge gene editing technologies (in vitro and in vivo) to explore mechanisms of tissue regeneration. Alongside this, the successful candidate will work with members of the HBF gene editing team to support relevant projects within the Francis Crick Institute.

The role of a Senior Laboratory Research Scientist at the Crick is diverse and rewarding. The role covers a wide range of different functions and allows for continuity of lab operations. The role offers support to one or more scientific projects or programmes.

Key Responsibilities

• Independently devising and leading gene editing projects within the TRCE research program
• Provision of technical and research expertise, as part of the HBF gene editing team, to assist in projects of other research groups
• Establishing new methodologies in the lab
• Maintaining laboratory organisation and supplies
• Training and supporting lab members in standard operating procedures
• Facilitating collaborations within and outside the Crick
• Provision of technical and research support in human stem cell biology including the tissue culture of pluripotent stem cells and organoids
• Human cell engineering encompassing molecular biology and CRISPR/Cas gene editing
• Management of regulatory protocols and research governance for the lab

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council, Cancer Research UK, Wellcome, UCL, Imperial College London and King’s College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it to the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

• If you are interested in applying for this role, please apply via the ‘Apply’ button above.
• All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.

Salary: £39,950 to £45,275 with benefits, subject to skills and experience