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Senior Drug Discovery Chemist

Hyper Recruitment Solutions Ltd

North East

On-site

GBP 100,000 - 125,000

Yesterday

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An established industry player is seeking a Senior Drug Discovery Chemist to join their innovative team in the North East. This role focuses on advancing antibody-drug conjugate (ADC) programs from early discovery to clinical development. You will design and synthesize novel therapeutic agents, optimizing linker technologies and payload selection. Collaborating with cross-functional teams, you will oversee multiple projects, ensuring timely progression through the drug discovery pipeline. If you have a strong background in organic chemistry and a passion for drug discovery, this is a fantastic opportunity to contribute to groundbreaking work in the pharmaceutical sector.

Relevant degree in Organic Chemistry or Medicinal Chemistry required.
Extensive experience in drug discovery, especially ADC development.

Design and synthesize novel ADCs with optimized linker technologies.
Collaborate with cross-functional teams to drive drug discovery programs.

Biological Sciences

Chemistry

Clinical Operations

Science

Degree in Organic Chemistry

Degree in Medicinal Chemistry

Synthetic Organic Chemistry Techniques

Bioconjugation Methods

14398Permanent Competitive Site Based North East - United Kingdom Updated on: 11-03-2025

We are currently looking for a Senior Drug Discovery Chemist to join a leading pharmaceutical company based in North East of England. As the Senior Drug Discovery Chemist, you will be responsible for advancing ADC programs from early discovery through to clinical development, contributing to the design and synthesis of novel therapeutic agents.

KEY DUTIES AND RESPONSIBILITIES:

Design and synthesize novel ADCs, focusing on optimizing linker technologies, payload selection, and bioconjugation strategies to enhance therapeutic index and tumour specificity.
Collaborate closely with cross-functional teams, including biology, pharmacology, and clinical development, to drive programs forward effectively.
Oversee multiple projects simultaneously, ensuring timely progression through the drug discovery pipeline.
Provide guidance and mentorship to junior chemists, fostering a culture of scientific excellence and innovation.

ROLE REQUIREMENTS:

Relevant degree in Organic Chemistry, Medicinal Chemistry, or a related discipline.
Extensive industry experience in drug discovery, with a strong emphasis on ADC development.
A working knowledge and practical experience with modern synthetic organic chemistry techniques, bioconjugation methods, and a deep understanding of linker and payload chemistry.

Key Words: Senior Drug Discovery Chemist / ADC Research / pharmaceutical / drug discovery / synthetic organic chemistry / bioconjugation / linker technologies / payload selection / oncology / clinical development

Hyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer. We welcome applications from anyone who meets the role requirements. HRS exclusively supports the Life Science sectors, combining recruitment expertise with scientific knowledge to help you advance your career.

Skills: Biological Sciences, Chemistry, Clinical Operations, Science

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