Scientist - Purification Development

Lonza Group Ltd.; Slough; On-site; GBP 60,000 - 80,000

Job description

Scientist - Purification Development

Location: Slough - Onsite Lab Based Role

Today, Lonza is a global leader in life sciences operating across five continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.

To develop, evaluate, characterise and validate protein purification processes for monoclonal antibodies and other recombinant proteins and support the transfer of these processes to pilot and GMP scale.

Key responsibilities:

• Plan and design own experiments with guidance from lead scientist
• Responsible for the execution and delivery of own projects with particular attention to safety, quality, on time and right first time
• Escalate technical issues in a timely fashion
• Ensure that experimental details, raw data and results are recorded appropriately
• Collate, analyse and evaluate data to produce good quality process information
• Operate as part of a cross-functional project team
• Prepare and deliver high quality presentations, protocols and reports
• Ensure own training is up to date
• Contribute to the efficient running of the laboratories

Key requirements:

• BSc / PhD in Biotechnology or in a relevant scientific discipline and appropriate laboratory experience.

Essential:

• Theoretical knowledge of protein chemistry and protein purification
• Strong practical laboratory skills
• Practical experience with laboratory scale AKTA chromatography and ultrafiltration (TFF) systems
• Strong written and verbal communication skills
• Strong planning and organisational skills
• IT proficient (i.e. Microsoft Office)
• Proficient in the use of Unicorn software

Desirable:

• Knowledge of GLP / GMP
• Experience of process transfer and scale up to cGMP manufacture
• Knowledge of GAP analysis methodologies (e.g. FMEA, Cause and effect analysis)
• Experience of process characterisation / validation
• Operational excellence (5S or similar) experience

Qualities and Attitude:

• Excellent attention to detail
• Must have excellent interpersonal skills to work effectively as part of a multidisciplinary/project team
• Prioritise and manage own time effectively
• Show initiative for problem solving and generating new ideas
• Work independently to an agreed plan
• Able to work with minimal supervision
• Comfortable working in a fast paced environment with changing priorities
• Willingness to support other activities within the department

Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.

People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.