Research Assistant - Protein Expression (12-Month FTC)

ZipRecruiter; London; On-site; GBP 30,000 - 50,000; Full time

Job description

Job Description

Job Title: Research Assistant – Protein Expression (12-Month Fixed-Term Contract)

Location: London, UK on-site full time

About the Company:

A leading biotechnology company dedicated to transforming cancer treatment. With a strong pipeline of complex biologics and a commitment to advancing oncology research, the company fosters a collaborative and dynamic environment for scientific discovery.

Role Overview:

An exciting 12 month FTC opportunity is available for a Research Associate in Protein Expression to support the in-house protein expression platform. The role involves the design, production, and optimization of recombinant proteins and antibodies, contributing to early-stage drug discovery and preclinical development.

Key Responsibilities:

• Design and construct plasmids for recombinant protein expression in suspension CHO/HEK cells, including antibodies, alternative formats, and antigens.
• Perform DNA amplification and purification from bacterial cells at various scales.
• Conduct transient expression of antibodies, ranging from milligram to gram scale.
• Produce antibodies from stable cell lines using fed-batch processes in mid-scale bioreactors.
• Explore and implement new technologies in protein expression.
• Maintain detailed records of experimental results and register expression batches.
• Collaborate with cross-functional teams.

Essential Qualifications & Experience:

• Industry experience in DNA purification at mini to giga scales.
• Proficiency in transiently expressing antibodies in CHO and/or HEK293 cells.
• Experience in optimizing expression titre and quality of antibodies and recombinant proteins.
• Familiarity with biomolecule tracking software such as Genedata Biologics.

Why Join?

• Be part of a pioneering team.
• Gain exposure to cutting-edge biotechnology in a supportive and dynamic environment.
• Work in a company committed to professional growth and inclusivity.

If you are a motivated and enthusiastic team player with a passion for protein expression and oncology research, we encourage you to apply.