Project Scientist 4 (Crystallization)

Cambrex Corp.; Penicuik, City of Edinburgh, Milton Bridge; On-site; GBP 35,000 - 55,000; Full time

Job description

Company Information

You Matter to Cambrex.

Cambrex is a leading global contract development and manufacturing organization (CDMO) that provides drug substance development and manufacturing across the entire drug lifecycle, as well as comprehensive analytical and IND enabling services.

With over 40 years of experience and a team of 2,000 experts servicing global clients from North America and Europe, Cambrex offers a range of specialized drug substance technologies and capabilities, including continuous flow, controlled substances, liquid-phase peptide synthesis, solid-state science, material characterization, and highly potent APIs.

Your Work Matters.

At Cambrex, we strive to build a culture where all colleagues have the opportunity to:

• engage in work that matters to our customers and the patients they serve
• learn new skills and enjoy new experiences in an engaging and safe environment
• strengthen connections with coworkers and the community

We’re committed to attracting and nurturing a passionate team of valued professionals in our fast-paced and growing company. We offer a competitive benefits package that includes healthcare, life insurance, planning for retirement, and more!

Your Future Matters.

Known for our customer-focused scientific and manufacturing excellence, as well as our strong commitment to quality and safety, we offer a range of career and growth opportunities across our global network of locations. Together with our customers, we aim to improve the quality of life for patients around the world. Start a career where You Matter by applying today!

Job Overview

The main purpose of the Crystallisation Scientist is to carry out crystallisation scale-up development projects to the highest technical standards, on the Active Pharmaceutical Ingredients (APIs) of SFS clients. These projects will be progressed from multi gram scale up to kilogram scale, where the process will be technology transferred to full scale manufacturing. Also, to facilitate closure of projects with minimal lead-time, whilst maintaining compliance to quality and safety systems, so that clients can progress development of their product / API.

Responsibilities

• The Crystallisation Scientist is responsible for the organisation and performance of all crystallisation process development projects including characterisation of samples generated and provided by clients. The crystallisation scientist is expected to deal with a demanding and unrelenting workload whilst maintaining a high standard of work. As such, they must be well organised and capable of prioritising and responding to a number of deliverables from a range of clients.
• The Crystallisation Scientist is expected to be competent in the underlying science of process and scale-up crystallisation, having experience of crystallisation pathways such as cooling crystallisation, anti-solvent crystallisation etc. at gram and ideally kg scale.
• The Crystallisation Scientist is expected to be experienced in using controlled lab reactors (CLRs) in conjunction with heater/chiller units and overhead stirrers to manipulate crystallisation systems to optimise: purities, yields, particle size distributions or any other client specific objectives.
• A working knowledge of current PAT technology is required, such as Blaze metric, FBRM, Raman and others. This is essential to understand and characterise the crystallisation system and MSZW (metastable zone width) for further optimisation and eventually technology transfer.
• The Crystallisation Scientist is expected to be competent in a wide variety of analyses using an extensive range of different techniques including specialist areas such as – DVS; XRPD; TG/DTA; DSC and more general areas including spectroscopic and wet chemistry methods.

Qualifications/Skills

• Possess excellent oral and written communication skills.
• Be well organised and able to manage high workloads.
• Able to meet deadlines and plan one’s own work effectively.
• Possess good problem-solving skills.
• Be commercially aware of business development needs.

Education, Experience & Licensing Requirements

• Masters / PhD in chemistry or chemical engineering.
• 2-5 years of experience preferred.
• Familiar with working within ISO9001 and/or cGMP quality standards.
• Experience in working independently and within a team in an R&D environment.
• Experience with working safely in a lab environment and adhering to local SHE policies.
• Able to participate in client meetings and discuss technical data clearly and succinctly.

Cambrex is committed to providing a safe and productive work environment. All offers of employment are contingent on the successful completion of a comprehensive pre-employment screen. The pre-employment screen may consist of several components including but not limited to a drug test, criminal record check, identity verification, reference checks, education and employment verification, and may vary based on federal, state, and local laws. Refusal to submit to testing will result in disqualification of further employment consideration.

All requirements are subject to possible modifications to reasonably accommodate individuals with disabilities. Cambrex Corporation is an Equal Opportunity / Affirmative Action employer and will consider all qualified applicants for employment without regard to race, color, religion, sex (including pregnancy, sexual orientation, or gender identity), ancestry, national origin, place of birth, age, marital status, disability/handicap, genetic information, veteran status, or other characteristics protected by federal, state, and/or local law.