Postdoctoral Fellow – Molecular Cell Biology of Autophagy lab

Francis Crick Institute; London; On-site; GBP 35,000 - 55,000

Job description

Postdoctoral Fellow – Molecular Cell Biology of Autophagy lab

Details of the role: Full-time, fixed term (4 Year) position on Crick terms and conditions of employment. Working pattern: Monday – Friday.

About us…

The Francis Crick Institute is Europe’s largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent, diagnose and treat illnesses such as cancer, heart disease, infectious diseases and neurodegenerative conditions.

The Crick is a place for collaboration, innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure, cutting-edge facilities, and a creative and curious culture. We’ve removed traditional boundaries of departments, divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality, pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.

About the role…

Work in the Tooze laboratory focuses on autophagy, a highly conserved cellular pathway that is essential for cell health and survival. Our research aims to understand how autophagy is initiated and regulated, focusing on the dedicated autophagy protein machinery. Our approach to discovery science relies on fundamental techniques used in molecular cell biology, biochemistry, and structural approaches. The focus of the work is increasingly directed toward understanding autophagy as a homeostatic regulator of cell responses to damage and stress originating from both internal and external changes.

You will be joining the lab as a Postdoctoral Fellow where you will be conducting independent research into these questions using mechanistic approaches in mammalian cells. You will be responsible for carrying out well-controlled, reproducible experiments which address a well-developed hypothesis. You will be joining an international group of highly motivated postdocs and PhD students with expertise in cell biology and structural biology, and will have access to state-of-the-art approaches and resources.

As a Postdoctoral Fellow you will lead on your own projects, contribute to other projects on a collaborative basis (both in the lab and with external collaborators) and may guide PhD students in their research. The ability to work in a team is essential.

If you have a PhD in Cell Biology, Molecular Biology, Biochemistry or a similar field, this may be the perfect opportunity for you to join the lab.

About you…

You will have

• PhD in Cell, Developmental, Molecular Biology or Biochemistry or in the final stages of PhD submission
• Relevant experience with developing iPSC cell models or other human cell models
• Good knowledge and experience in autophagy, molecular biology and biochemistry
• Track record of productive research as evidenced by publications or submitted manuscripts
• Evidence of data presentation at scientific meetings

What will you receive?

At the Francis Crick Institute, we value our team members and are proud to offer an extensive range of benefits to support their well-being and development:

• Visas: Applicants for this role will be eligible for sponsorship to work in the UK
• Generous Leave: 28 days of annual leave, plus three additional days over Christmas and bank holidays.
• Pension Scheme: Defined contribution pension with employer contributions of up to 16%.
• Health & Well-being:
• 24/7 GP consultation services.
• Occupational health services and mental health support programs.
• Eye care vouchers and discounted healthcare plans.
• Work-Life Balance:
• Back-up care for dependents.
• Childcare support allowance.
• Annual leave purchase options.
• Crick Networks offering diverse groups’ support, community and inclusive social events.
• Perks:
• Discounted gym memberships, bike-to-work scheme, and shopping discounts.
• Subsidised on-site restaurant and social spaces for team interaction.
• Development & Recognition: Comprehensive training, mentoring, and a pay structure with performance-linked progression.

Equality, Diversity & Inclusion:

We welcome applications from all backgrounds. We are committed to providing equal employment opportunities, regardless of ethnicity, nationality, gender, sexual orientation, gender identity, religion, pregnancy, age, disability, or civil partnership, marital or family status. We particularly welcome applications from people who are Minority Ethnic as they are currently underrepresented in the Crick at this level.

Diversity is essential to excellence in scientific endeavour. It increases breadth and perspective, leading to more innovation and creativity. We want the Crick to be a place where everyone feels valued and where diversity is celebrated and seen as part of the foundation for our Institute’s success.