Head of Technical Transfer

Upperton Pharma Solutions; West Yorkshire; On-site; GBP 40,000 - 80,000; Full time

Job description

Upperton Pharma Solutions is a leading Nottingham-based contract development and manufacturing organisation (CDMO) specialising in formulation development, clinical trial manufacturing and manufacturing services for a wide range of dosage forms, including oral solids, liquids, semi-solids, and inhalation products.

With state-of-the-art facilities and a team of experienced scientists, Upperton offers tailored solutions to accelerate drug development from concept to commercialisation. Upperton is committed to innovation, quality, and shares in our customers' dedication to changing the lives of patients.

Upperton collaborates closely with global pharmaceutical and biotech companies to bring novel therapies to market efficiently and effectively.

Continued growth and investment into the business has led to the creation of exciting new job opportunities in our new GMP Manufacturing headquarters in Beeston, Nottingham. Upperton Pharma Solutions is undergoing a period of significant expansion to meet international customer demand and offer a comprehensive drug development portfolio, so now is a great time to join our team.

The Head of Technical Transfer is responsible for all GMP and Non-GMP manufacturing operations, including but not limited to process development, scale up, technical batch manufacture and technical transfer activities. The post holder's responsibilities will also include operational activities within the Unit 3 manufacturing facility and equipment for which these operations are conducted. The role will have direct line management responsibility for operational staff within these functional areas. The post holder will ensure that all operations are developed and conducted within the framework of the Upperton Pharma Solutions Quality Management System and that the facility and operation are qualified to meet the regulatory requirements as set out by regulatory authorities. The post holder will also be responsible for building operational capabilities for commercial manufacturing.

Main Duties And Responsibilities

1. Ensure that all manufacturing operations within the GMP and non-GMP facilities are fully compliant with the regulatory requirements.
2. Ensure that all manufacturing operations within the GMP and non-GMP facilities are fully compliant with the Upperton Quality System.
3. Facilitate the development and qualification of all processes and systems relevant to technical transfer operations within Upperton.
4. Lead facility tours for client visits/audits and regulatory inspections.
5. Responsible for the implementation of the Upperton Quality system in the GMP facility.
6. Ensuring that all activities and outputs meet the Upperton quality system.
7. Direct all scale up and technical transfer activities to ensure that project deliverables and targets are successfully met and are of the highest quality.
8. Manage and develop the technical transfer team and be responsible for their performance, training and regular appraisal.
9. Responsible for the GMP facility (including environmental controls), equipment and all process qualification/validation/simulation.
10. Ensure that all documentation emanating from the GMP facility meets the requirement of the Upperton Quality system including operating records, batch manufacturing records and project reports.
11. Participate in customer contacts and business planning with the Associate Director and Director of Manufacturing.
12. Track project activities from a commercial perspective. Ensure that commercial deliverables are tracked and fully met.
13. Liaise with Project Management and Finance to ensure that correct invoices are sent out on time.
14. Provide critical support and focus on projects, focusing on technical transfer and process scale up activities conducted both internally at Upperton and for projects outsourced to third party vendors.

Essential Skills And Experience

1. Proven leadership and management skills with the ability to optimise team performance and development.
2. Excellent relationship management skills with the ability to engage, negotiate and manage key stakeholders across internal departments.
3. Excellent communication, interpersonal and influencing skills.
4. Excellent analytical and problem solving abilities.
5. Results orientated with ability to plan and deliver against project deadlines.
6. Commercially and financially astute with experience of managing budgets.
7. Resilient, self-motivated and able to work well under pressure.
8. Technical mindset.
9. An appreciation of and an ability to positively resolve issues.

What You Will Get In Return

We offer employees not only a competitive salary but also an excellent suite of benefits including:

• 25 days holiday and your birthday off!
• Company contributory pension package.
• Life insurance.
• Private Medical Insurance through Vitality.
• Internal and external training courses and professional development support.
• Free onsite car parking.

We know it is the little things that make every day special, so we also organise employee events for you to attend throughout the year, like our annual Christmas party, summer party and charity fundraising events.