GMP Production Biotechnologist

We want you to feel inspired every day. We are future-focused and our business is growing. We succeed together through passion, commitment, and teamwork, and so can you.

We are looking for motivated people to work as Biotechnologists who want to make a difference, delivering advanced innovative treatments to patients with unmet needs and join us at one of our facilities. The purpose of the role is manufacturing commercial and clinical grade viral vector batches within a GMP cleanroom facility.

Our manufacturing team is a critical part of Oxford Biomedica’s operations. We produce multiple clinical and commercial lentiviral vector-based gene therapy products, across seven cleanroom suites in Oxford.

We have opportunities at our Transport Way, Oxbox and Yarnton Facilities.

Your responsibilities in this role would be:

• Largescale manufacture of ATMPs within GMP cleanroom facilities including:
  • Upstream adherent and/or suspension mammalian cell culture, transfection and harvest of viral vector products.
  • Downstream processing including clarification, chromatography, ultra/diafiltration and fill/finish activities.
• Ensuring batch success by working using good aseptic techniques.
• Preparing, cleaning and maintaining the GMP facility including performing viable and non-viable environmental monitoring.
• Preparation of growth media and stock solutions using portable mixing tanks.
• Completing Batch Manufacturing Records in a timely fashion throughout the manufacturing process.
• Taking part in continuous improvement initiatives & development of production processes.
• Investigating quality incidents, deviations and improving procedures.
• Working to high standards of health & safety.

We are looking for:

• Working within a GMP manufacturing environment is advantageous but not essential.
• Degree level qualification.
• Prior experience of working within an aseptic environment is advantageous but not essential.
• Self-motivated with a strong focus on safety, quality, details, and results.
• Good problem solving, interpersonal communication and team skills.
• Excellent writing skills and computer literacy.
• Flexibility to work shifts.

About Us:

OXB is a quality and innovation-led viral vector CDMO with a mission to enable its clients to deliver life changing therapies to patients around the world. One of the original pioneers in cell and gene therapy, we have more than 25 years of experience in viral vectors; the driving force behind the majority of gene therapies.

OXB collaborates with some of the world’s most innovative pharmaceutical and biotechnology companies, providing viral vector development and manufacturing expertise in lentivirus, adeno-associated virus (AAV) and adenoviral vectors. OXB’s world-class capabilities span from early-stage development to commercialisation. These capabilities are supported by robust quality-assurance systems, analytical methods, and depth of regulatory expertise.

What’s in it for you:

• Highly competitive total reward packages
• Wellbeing programmes
• Development opportunities
• Welcoming, friendly, supportive colleagues
• A diverse and inclusive working environment
• Our values are: Responsible, Responsive, Resilient, Respect
• State of the art laboratory and manufacturing facilities

Collaborate. Contribute. Change lives.