Greater London
On-site
GBP 30,000 - 50,000
9 days ago
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An established industry player is seeking a motivated individual to join their dynamic team in the field of biotherapeutics. This role involves conducting in vitro transcription and RNA purification, performing quality control assays, and executing cell-based assays. The ideal candidate will have a strong educational background in molecular biology or a related field, complemented by hands-on experience in nucleic acid preparation and purification techniques. This is an exciting opportunity to contribute to innovative therapeutic programs while working in a collaborative environment that values detail-oriented and resourceful team members. If you are passionate about advancing genetic medicine, this position is perfect for you.
- MS in molecular biology or related field with 0-2 years experience, or BS with 3-5 years.
- Hands-on experience with nucleic acid preparation and cell-based assays is essential.
- Conduct in vitro transcription and RNA purification for therapeutic programs.
- Perform cell-based assays and maintain electronic laboratory notebooks.
Nucleic acid preparation
Quality control assays
Cell culture
Data analysis
Problem-solving skills
Written communication
Oral communication
MS in molecular biology
BS in related field
AKTA
SnapGene
Prism
FlowJo
Excel
PowerPoint
Responsibilities
- In vitro transcription to produce mRNA at different scales to support the platform development and therapeutic programs.
- RNA Purification using affinity chromatography (AKTA) and other strategies for purification.
- Quality control assays for mRNAs like electrophoresis, ELISA, qPCR, etc.
- Perform cell-based assays, such as cell culture, transfection, and flow cytometry.
- Work closely with the manager and cross-functional team members on multiple tasks with the ability to analyze, interpret, and present data.
- Assist in ordering reagents from internal and external suppliers and communicating with CROs.
- Generate reliable and reproducible data in a timely manner.
- Read and adapt scientific literature to accomplish assignments. Demonstrate broad and versatile technical expertise within discipline.
- Maintain electronic laboratory notebooks (ELN) in compliance with the Company Laboratory Notebook Policy.
- Stay updated and in compliance on all departmental and corporate training.
Requirements
- MS in molecular biology, biochemistry, biomedical engineering, or related field with 0-2 years of experience in biotherapeutics or genetic medicine or BS with a minimum of 3-5 years of relevant industry experience.
- Hands-on experience with nucleic acid preparation, purification (AKTA), QC, and cell-based assays.
- Working knowledge of related tools/software (SnapGene, Prism, FlowJo, Excel, PowerPoint etc.).
- Self-motivated, hard-working, detail-oriented, resourceful, and able to work in a fast-paced team environment with demonstrated problem-solving skills.
- High-quality written and oral communication skills and the ability to excel in a collaborative environment.