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Scientist II

Katalyst CRO

Greater London

On-site

GBP 30,000 - 50,000

9 days ago

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Job summary

An established industry player is seeking a motivated individual to join their dynamic team in the field of biotherapeutics. This role involves conducting in vitro transcription and RNA purification, performing quality control assays, and executing cell-based assays. The ideal candidate will have a strong educational background in molecular biology or a related field, complemented by hands-on experience in nucleic acid preparation and purification techniques. This is an exciting opportunity to contribute to innovative therapeutic programs while working in a collaborative environment that values detail-oriented and resourceful team members. If you are passionate about advancing genetic medicine, this position is perfect for you.

Qualifications

  • MS in molecular biology or related field with 0-2 years experience, or BS with 3-5 years.
  • Hands-on experience with nucleic acid preparation and cell-based assays is essential.

Responsibilities

  • Conduct in vitro transcription and RNA purification for therapeutic programs.
  • Perform cell-based assays and maintain electronic laboratory notebooks.

Skills

Nucleic acid preparation

Quality control assays

Cell culture

Data analysis

Problem-solving skills

Written communication

Oral communication

Education

MS in molecular biology

BS in related field

Tools

AKTA

SnapGene

Prism

FlowJo

Excel

PowerPoint

Job description

Responsibilities
  • In vitro transcription to produce mRNA at different scales to support the platform development and therapeutic programs.
  • RNA Purification using affinity chromatography (AKTA) and other strategies for purification.
  • Quality control assays for mRNAs like electrophoresis, ELISA, qPCR, etc.
  • Perform cell-based assays, such as cell culture, transfection, and flow cytometry.
  • Work closely with the manager and cross-functional team members on multiple tasks with the ability to analyze, interpret, and present data.
  • Assist in ordering reagents from internal and external suppliers and communicating with CROs.
  • Generate reliable and reproducible data in a timely manner.
  • Read and adapt scientific literature to accomplish assignments. Demonstrate broad and versatile technical expertise within discipline.
  • Maintain electronic laboratory notebooks (ELN) in compliance with the Company Laboratory Notebook Policy.
  • Stay updated and in compliance on all departmental and corporate training.
Requirements
  • MS in molecular biology, biochemistry, biomedical engineering, or related field with 0-2 years of experience in biotherapeutics or genetic medicine or BS with a minimum of 3-5 years of relevant industry experience.
  • Hands-on experience with nucleic acid preparation, purification (AKTA), QC, and cell-based assays.
  • Working knowledge of related tools/software (SnapGene, Prism, FlowJo, Excel, PowerPoint etc.).
  • Self-motivated, hard-working, detail-oriented, resourceful, and able to work in a fast-paced team environment with demonstrated problem-solving skills.
  • High-quality written and oral communication skills and the ability to excel in a collaborative environment.
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