Research Technician

University of Glasgow; Glasgow; On-site; GBP 26,000 - 31,000

Job description

The School of Infection and Immunity is seeking an experienced Research Technician to support research activities in molecular microbiology and bacterial genetics under the supervision of Dr Arianne Babina (Principal Investigator).

Job Purpose

The successful candidate will provide technical expertise in molecular microbiology and bacterial genetics, contributing to experiments, lab management, and supervision and training of team members to support ongoing research. They will contribute to short-term research projects and collaborate as part of larger research teams. Additionally, they will perform a range of technical support activities aligned with the School’s research strategy.

The Babina Lab uses microbiology, molecular genetics, biochemistry, experimental evolution, and large-scale “-omics” approaches to investigate how novel bacterial gene regulatory networks emerge and evolve to help bacteria rapidly adapt to environmental changes. Our research particularly focuses on the de novo emergence of novel gene regulatory mechanisms, such as non-coding RNAs and small proteins, from previously non-functional or non-coding DNA sequences.

Main Duties and Responsibilities

1. Provide technical and research support for ongoing research projects in the lab.
2. In liaison with the PI, advise, implement and evaluate improvements to existing protocols relevant as required.
3. Collect, analyse and interpret data using standard procedures and ensure that accurate research records are kept, and databases are updated accordingly.
4. Plan and organise day to day work to ensure that the experimental goals are delivered within previously agreed timescales.
5. To supervise junior staff, where appropriate, and instruct, train and provide guidance to research staff and students in the techniques and operation of equipment and apparatus as directed by the supervisor, lab manager or PI.
6. Contribute to the well organised functioning of the laboratory by assisting the PI in maintaining equipment, managing stock levels, and purchasing consumables and supplies within budget, in coordination with other group members.
7. In consultation with the PI and floor coordinator, ensure the safe and efficient functioning of the laboratory area and facilities. This includes, but is not limited to, supporting the completion of risk assessments and COSHH assessments, ensuring that all Health and Safety paperwork is completed timeously and recorded accurately, and implementing and adhering to health and safety policies, as determined by the University and the Health and Safety Executive.
8. Collaborate with colleagues and participate in team meetings/discussions and departmental research group activities.
9. Keep up to date with advancements in technology and methodology, continually updating technical knowledge.
10. Be aware of and comply with Equality and Diversity policies of the University of Glasgow. The above duties are not exhaustive, and the post-holder will be required to undertake any other relevant duties as required by the PI/line manager which are commensurate with the grade of the post.

Knowledge/Qualifications, Skills and Experience

Knowledge/Qualifications

Essential:

1. A1. Scottish Credit and Qualifications Framework level 7 (Advanced Higher / HNC, SVQ 3), or equivalent in relevant science subject.
2. A2. Detailed technical knowledge of molecular biology, microbiology, and bacterial genetics.
3. A3. Up to date knowledge of relevant laboratory Health and Safety legislation.

Desirable:

1. B1. Scottish Credit and Qualifications Framework level 9 (BSc Degree, SVQ Level 4) or equivalent in relevant scientific discipline.
2. B2. Knowledge of Equality and Diversity policy.

Skills

Essential:

1. C1. Experience in practical laboratory techniques in molecular biology and microbiology, including reagent and media preparation, sterile technique, bacterial culture, PCR, and molecular cloning.
2. C2. Computer skills including familiarity with Microsoft Office and relevant databases.
3. C3. Demonstrable analytical and problem-solving abilities.
4. C4. Proven interpersonal and communication skills.
5. C5. Numeracy and literacy skills.
6. C6. A high level of accuracy and attention to detail.
7. C7. Excellent organisational and time management skills and an ability to prioritise workload to meet competing demands.
8. C8. Use of initiative and judgement to resolve problems independently.
9. C9. Ability to work individually and as part of a team.

Desirable:

1. D1. Ability to design primers and analyse Sanger sequencing data.
2. D2. Proficiency in designing and constructing recombinant bacterial strains.
3. D3. Competence in RNA extraction and qPCR techniques.
4. D4. Proficiency in protein analysis techniques.

Experience

Essential:

1. E1. Extensive relevant work experience (i.e. greater than 1 month) in a research laboratory setting.
2. E2. Proficient in core molecular biology and microbiology techniques, including the preparation of reagents and media, as well as expertise in sterile technique, bacterial culture, PCR, and molecular cloning.
3. E3. Proven experience in learning, executing, and adapting experimental protocols effectively.

Desirable:

1. F1. Demonstrated leadership experience, such as the ability to train and supervise others.
2. F2. Experience in the design and construction of recombinant bacterial strains, such as Lambda-Red recombination and phage transduction.
3. F3. Experience in conducting and analysing bacterial growth assays.
4. F4. Experience in developing, optimizing, and executing reporter gene assays.
5. F5. Familiarity with RNA and/or protein-related techniques.

Terms and Conditions

Salary will be Grade 5, £26,338 - £30,805 per annum.

This post is full time (35 hours per week) and open ended with funding available for up to 24 months from start date.

Please note, due to limited funding availability, we will be able to offer a salary at the first spinal point of Grade 5 (£26,338) only.

Any informal enquiries on this post may be directed to Dr Arianne Babina via email ([e-mail])

Closing date: 23:45 on Wednesday 30th April 2025.