Discovery Disease Area Lead - Hepatology

Discovery Disease Area Lead - Hepatology, Stevenage

Client:

GSK

Location:

Job Category:

Other

EU work permit required:

Yes

Job Reference:

4cae031c8da1

Job Views:

10

Posted:

15.04.2025

Expiry Date:

30.05.2025

Job Description:

Job Title: Discovery Disease Area Lead, Hepatology

Company Overview: At GlaxoSmithKline (GSK), we are dedicated to improving the quality of human life by leveraging scientific advancements to develop better medicines with reduced attrition.

Job Purpose: As the Discovery Disease Area Lead, Hepatology, you will be at the forefront of our mission, driving the discovery and validation of therapeutic targets for a range of chronic diseases such as MASH, NAFLD, and ALD. You will lead a cross-functional team of scientists, clinical staff, and pharma experts to identify and validate high-quality targets using large-scale experimental and in silico approaches.

Key Responsibilities:

1. Portfolio Execution:
   1. Portfolio Generation and Oversight: Generate and oversee the pre-Commit to Target (C2T) project portfolio in the Hepatology therapy area.
   2. Target Delivery: Regularly deliver pools of high-potential targets that fulfill all C2T quality criteria.
   3. Senior Management Interface: Influence Senior R&D management by identifying and communicating portfolio risks and opportunities.
   4. Strategy Execution: Drive development and implementation of key components of the hepatology research strategy.
   5. Team Representation: Ensure appropriate representation of lines/functions within the operational matrix team.
2. Hepatology Expertise:
   1. Hepatology Expertise: Apply deep experience in hepatology disease indications drug discovery.
   2. Scientific Excellence: Drive best-in-class science across Research Technologies and Research Units.
   3. Strategic Partnership: Partner proactively with Research Units and Research Technology Leadership.
   4. External Engagement: Maintain connection with hepatology experts and societies.
   5. Clinical Insight: General understanding of clinical treatments for MASH, NAFLD, and ALD.
   6. Business Case Development: Lead the creation of strong business cases that align with RU and RTech strategies.
   7. External Opportunities Assessment: Collaborate with Business Development to assess external opportunities.
3. Strategic Alignment:
   1. Framework Adherence: Ensure adherence to decision frameworks up to C2T.
   2. Resource Coordination: Coordinate resources from RTech and RUs.
   3. Risk Management: Elevate resource challenges, project risks, and opportunities.
   4. Resource Allocation: Make recommendations to department heads on areas to reduce, postpone, or stop.

Basic Qualifications:

• Education: Minimum of an MD or PhD degree or extensive drug discovery and development experience.
• Experience: Significant progressive pharmaceutical experience required.
• Leadership Skills: Proven track record of exceptional team and cross-functional leadership.
• R&D Expertise: Experience with hepatology R&D programs.
• Research Program Design: Ability to design a comprehensive drug discovery program.

Preferred Qualifications:

• Data Interpretation: Strong data interpretation and report/presentation writing skills.
• Global Mindset: Demonstrated ability to assimilate complex science quickly.
• Cross-functional Collaboration: Ability to work cross-functionally and with high-level managers.
• Communication Skills: Excellent executive communication skills.
• Time Management: Ability to manage multiple demands and priorities.
• Networking: Access to internal and external networks of experts.

Why GSK?

GSK is a global biopharma company with a special purpose – to unite science, technology, and talent to get ahead of disease together.

Our success absolutely depends on our people. We want GSK to be a place where people feel inspired, encouraged, and challenged to be the best they can be.

As an Equal Opportunity Employer, we are open to all talent.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.