Clinical Research Fellow - Lymphoma

Manchester University NHS Foundation Trust; Manchester; On-site; GBP 80,000 - 100,000; Full time

Job description

Job Summary

We seek an ambitious, innovative individual with a specific interest in lymphoma, clinical research and/or early phase clinical trials to act as sub-investigator for a growing portfolio of complex clinical trials. The role offers an exciting opportunity to work with an established, multidisciplinary research team to deliver innovative research. With consultant oversight, you will be responsible for seeing new referrals, follow-ups & managing patients throughout all aspects of their trial experience. You will take an active role in local and regional meetings to identify and define suitable trial options for patients. You will also be involved with managing NHS patients through our lymphoma clinics, with approximately 50% of your time being dedicated to research, professional development and teaching. This is a 10 session non-training post. It is suitable for individuals post-FY2 through to those completing specialist training in Oncology or Haematology, and who wish to gain further experience in lymphoma alongside experimental medicine and early-phase trials, including first-in-human trials, advanced immunotherapies and translational research. Applicants must be able to start early August 2025; applicants requiring GMC sponsorship via MTI recruitment processes will not be considered on this occasion. Salary will be on the NHS scale in line with appropriate clinical experience. Interested candidates are encouraged to discuss this ahead of any application.

Main duties of the job

The portfolio includes a diverse range of lymphoma clinical trials. Following training, you will be expected to participate in these studies as a sub-investigator and associate principal investigator. These include phase I-III trials of small molecule inhibitors, next-generation chemotherapy, novel immunotherapies, CAR-T-cell therapy and translational studies. You will be involved in managing all aspects of lymphoma trial patients (both in outpatient & inpatient settings), through new patient consultation, consent & screening patients & reviewing patients at follow-up appointments. You will be expected to attend safety review committee meetings to discuss trial patients. This will involve close liaison with the Principal Investigators. In addition, you will interface with external stakeholders such as CROs & pharmaceutical sponsors. You will be expected to undertake the administrative duties associated with the care of our patients. You will be given opportunities and will be encouraged to be involved in the development & planning of new studies. Up to 50% of your time will be dedicated to lymphoma research, with scope to develop a range of projects according to personal interests. You will be expected to be involved in writing papers & reviews, and there is potential to present your research work nationally and internationally. Participation in established clinical research training schemes will be encouraged. You will also be required to undergo an annual appraisal.

About Us

The Christie is one of Europe's leading cancer centres, treating over 60,000 patients per year. We are based in Manchester and serve a population of 3.2 million across Greater Manchester & Cheshire, but as a national specialist around 15% patients are referred to us from other parts of the country. We provide radiotherapy through one of the largest radiotherapy departments in the world; chemotherapy on site and through 14 other hospitals; highly specialist surgery for complex and rare cancer; and a wide range of support and diagnostic services. We are also an international leader in research, with world first breakthroughs for over 100 years. We run one of the largest early-phase clinical trial units in Europe with over 300 trials every year. Cancer research in Manchester, most of which is undertaken on the Christie site, has been officially ranked the best in the UK. The lymphoma team have the largest portfolio of both commercial and non-commercial lymphoma trials in the UK. You will support an established, dynamic, multidisciplinary research team to deliver innovative treatments to patients from a wide geographic area. You will be supported to develop and advance your own research skills and interests.

Person Specification

Qualifications Essential

• MRCP or equivalent - Qualification details and pass dates should be confirmed in the supporting information
• GMC registration

Training Essential

• ICH GCP Training

Experience Essential

• Minimum of 2 years' clinical practice, with experience in Medical/Clinical Oncology and/or Haemato-oncology
• Experience as an investigator on clinical trials

Personal skills Essential

• Evidence of clinical leadership skills
• Ability to work flexibly as part of a team
• Excellent written and oral communication skills
• Ability to work under pressure
• Capacity for staff motivation
• Reliable work record