Analytical Chemist, Mass Spectrometry

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Site Name: UK - Hertfordshire - Stevenage
Posted Date: Dec 10 2024

We create a place where people can grow, be their best, be safe, and feel welcome, valued, and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

We embrace modern work practises; our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.

Discover more about our company wide benefits and life at GSK on our webpage Life at GSK | GSK.

Analytical Chemist - Mass Spectrometry

Job Purpose

We are seeking a highly skilled and motivated analytical chemist with a strong background in mass spectrometry to join our Analytical Chemistry team. The successful candidate will be responsible for developing and implementing mass spectrometry-based methods for the analysis of a range of sample types from small molecules to new modality compounds, including oligonucleotides (oligos) and antibody-drug conjugates (ADCs). This role requires a strong background in mass spectrometry, method development, and a deep understanding of the unique challenges associated with analysing these complex molecules.

In this role you will

1. Develop, optimize, and validate mass spectrometry-based analytical methods for the characterization of novel chemical entities, including small molecules, protacs, oligonucleotides and antibody drug conjugates (ADCs).
2. Investigate and implement novel technologies and improvements to methodologies to enhance capabilities.
3. Perform routine and non-routine mass spectrometric analyses to support research projects.
4. Collaborate with cross-functional teams, including medicinal chemistry and modality platforms to provide analytical support and contribute to project goals.
5. Troubleshoot and resolve technical issues related to mass spectrometry and associated instrumentation and methods. Maintain and calibrate mass spectrometry instruments to ensure accurate and reliable data.
6. Document and interpret experimental results, prepare technical reports, and present findings to key stakeholders.
7. Stay current with advancements in mass spectrometry technologies and methodologies relevant to the analysis of new modality compounds.
8. Ensure compliance with all relevant regulatory guidelines and GSK's quality standards.

Why you?

Basic Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals:

1. BSc in Chemistry, Biochemistry, or a related field and demonstrated experience using mass spectrometry.
2. Strong understanding of the principles of mass spectrometry, including ionization techniques, fragmentation patterns, and data interpretation.
3. Proficient in using mass spectrometry data analysis software and tools.
4. Strong communication skills, both written and verbal, with the ability to present complex data to diverse audiences.
5. Ability to work both independently and effectively in a collaborative, team-oriented environment.
6. Excellent problem-solving skills and the ability to troubleshoot technical issues independently.

Preferred Qualifications & Skills:

Please note the following skills are not necessary, just preferred; if you do not have them, please still apply:

1. Ph.D. in Analytical Chemistry, Chemistry, or a related field with a focus on mass spectrometry, or a Master's degree with significant relevant experience.
2. Extensive hands-on experience with mass spectrometry instrumentation, including TOF mass spectrometers.
3. Proven track record in developing and validating mass spectrometry-based methods for complex molecules, preferably oligonucleotides and ADCs.
4. Experience with method development of associated chromatographic techniques such as LC, UPLC, and RapidFire.

Closing Date for Applications: 10/01/25

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/immunology, and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged, and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state, or local protected class (US only).