Senior Analytical Scientist – Chromatography

Senior Analytical Scientist – Chromatography

Role Overview

As a Senior Analytical Scientist, you will lead the development, optimization, and implementation of robust analytical methods using UPLC/HPLC systems. Your expertise will directly support development projects by ensuring data integrity, compliance, and adherence to regulatory standards.

Key Responsibilities

• Analytical Method Development: Design and conduct experiments to create reliable chromatographic methods, employing risk assessment and Quality-by-Design (QbD) principles when applicable.
• Data Analysis: Compile, interpret, and present scientific data to guide decision-making and ensure method robustness.
• Project Management: Oversee experiments and ensure timely completion, either independently or by coordinating with team members.
• Documentation & Compliance: Develop, validate, and document chromatographic methods in alignment with company quality standards and ICH guidelines.
• Technical Writing: Write, update, and review SOPs related to equipment use and analytical procedures.
• Collaboration: Actively collaborate with cross-functional teams, such as R&D, regulatory affairs, and process development, to meet project objectives.
• Knowledge Transfer: Support the transfer of analytical methods to internal teams or external partners (e.g., CDMOs).
• Continuous Improvement: Drive lab process improvements, adopt best practices, and expand analytical capabilities by evaluating new technologies.
• Client Interaction: Participate in client meetings and teleconferences, effectively communicating in English.

Qualifications

• MSc in Analytical Chemistry, Chemistry, or a related field, with at least 5 years of experience in UPLC/HPLC method development and pre-validation within an R&D setting.
• Proficient in using Empower3 software.
• Knowledge of DoE methodologies (e.g., S-Matrix Fusion QbD or similar software) is advantageous.
• Familiarity with QbD principles for analytical method development and validation is a plus.
• Understanding of complementary analytical techniques, particularly mass spectrometry (MS), is desirable.
• Experience working in GMP/GLP-compliant environments and knowledge of ICH guidelines is an asset.
• Strong scientific curiosity and analytical expertise.
• Hands-on experience with analytical instrumentation and methods.
• Proficiency in basic statistical analysis and experimental design.
• Problem-solving skills and the ability to make sound technical decisions.
• Excellent organizational and project management capabilities.
• Effective written and verbal communication skills in English; proficiency in French is a strong advantage.
• Familiarity with writing scientific documents and working in an international environment is preferred.
• Cross-border educational or professional experience is a plus.