(FL-817) - Researchercomputational Design Gene Editors

The Institute
The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed of an interdisciplinary, motivated and creative scientific team supported by a flexible and efficient administration and high-end innovative technologies. In April 2021, the Centre for Genomic Regulation (CRG) received the renewal of the 'HR Excellence in Research' Award from the European Commission. This is a recognition of the Institute's commitment to developing an HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers (Charter and Code). Please check out our Recruitment Policy.

The role
The main responsibilities will include implementing and using machine learning models for the design of gene writer sequences.

About the team

Whom would we like to hire?

1. Professional experience
   Must Have:
   • Experience in bioinformatics, computational structural biology, or computational biology
   • Good understanding of software engineering and good code practices
   • The capability of working independently on very fast-paced science
2. Desirable but not required/ Nice to have:
   • PhD in Bioinformatics, Synthetic Biology or a related field
   • Experience in protein or enzyme design
   • Knowledge about gene editing technologies such as CRISPR‐associated nuclease‐based tools

Education and training
MSc in Biotechnology, Computer Science, Chemistry, Physics, Maths or a related discipline.

Languages
Good communication skills in English.

Competences
Self-motivated, capability of working independently.

Technical Skills
Linux, python programming, knowledge of computational structural biology (protein visualization and modelling, multiple sequence alignment), knowledge about writing scientific publications (e.g., figure preparation), knowledge of data analysis with python (pandas, huggingface, pytorch); handling environments with conda, pyenv; use of scientific clusters (slurm).

The Offer
- Contract duration: Technical and scientific activities contract linked to the project (estimated 3 years)
- Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales
- Target start date: As soon as possible

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section.

We offer and promote a diverse and inclusive environment and welcome applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation, or gender identity.

The CRG is committed to reconciling work and family life for its employees and is offering an extended vacation period and the possibility to benefit from flexible working hours.