Bioinformatician at Cellular & Systems Neurobiology group

Bioinformatician at Cellular & Systems Neurobiology group

The Institute

The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed of an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.

We are looking for a Bioinformatician at the Cellular and Systems Neurobiology lab to work on the project titled “Psych-STRATA - A Stratified Treatment Algorithm in Psychiatry: A program on stratified pharmacogenomics in severe mental illness” funded by European Union’s HORIZON-HLTH-2021 program under grant agreement No 101057454 and led by Dr Mara Dierssen.

The position requires a candidate with previous experience in Bioinformatics. The candidate will process and analyse multi-omics datasets (eg. RNA-Seq, smallRNA-Seq, proteomics). The candidate will design and apply integrative data analysis (computational/statistical/causal) and visualization techniques for multi-omic (transcriptomics, mirnomic and proteomics) data to address research hypotheses. The candidate will apply machine learning models to clinical and omics data for classification tasks. The candidate will also acquire knowledge to analyse spatial transcriptomic data. We are looking for highly motivated and organized candidates with good communication skills, capable of working in a group but also with a high degree of work autonomy.

About the lab

The Dierssen lab is centred on understanding cognition and behaviour and their perturbation in intellectual disability. We are an interdisciplinary team of physicists, bioinformaticians and experimental biologists, and we focus on data collection (behaviour, 3D imaging, genomic data) of many variables of the system (longitudinal behavioural analysis, population-based analysis in neuronal networks, gene expression patterns). We take advantage of computer modelling and bioinformatics analysis (gene networks, neuronal network modelling, etc.) to tackle classical unresolved questions in the field.

Whom would we like to hire?

Professional experience

Must Have

1. You have at least 2 years of experience as a bioinformatician in an area involving Neuroscience.
2. You have proven experience in big data analysis (RNASeq, smallRNASeq, GWAS, proteomics).
3. You have excellent understanding of transcriptomic and proteomic workflows, data structure and potential data analysis approaches to efficiently integrate and/or develop analysis and visualization protocols.
4. You have experience in analyzing, integrating and harmonizing multi-omics datasets e.g., using network-based, graph modelling, dimensionality reduction or machine learning approaches.
5. You can process and derive novel insights from integrative analysis of multi-omic datasets.

Desirable but not required/ Nice to have

Previous experience in neuropsychiatric research will be an added value.

Education and training

You hold a PhD in Neuroscience, Bioinformatics, Genomics, Data Science, or related fields.

Languages

Good spoken and written English.

Technical skills

1. You have proficiency in R or Python for data analysis and programming.
2. Solid knowledge of UNIX-like operating systems and shell scripting.
3. You have knowledge in advanced statistics and machine learning.

Competences

Highly developed organizational skills. A highly motivated and organized candidate, capable of working in a group, and with a high degree of work autonomy.

The Offer – Working Conditions

Contract duration: 6 months, temporary contract.

Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales.

We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section.

We offer and promote a diverse and inclusive environment and welcome applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.

The CRG is committed to reconciling a work and family life of its employees and is offering an extended vacation period and the possibility to benefit from flexible working hours.

Application Procedure

All applications must include:

1. A motivation letter addressed to Dr Mara Dierssen.
2. Contact details of two referees.

All applications must be addressed to Dr. Mara Dierssen and be submitted online through the "Apply" button below.

Selection Process

Pre-selection: The pre-selection process will be based on qualifications and expertise reflected in the candidates' CVs. It will be merit-based.

Interview: Preselected candidates will be interviewed by the Hiring Manager of the position and a selection panel if required.

Offer Letter: Once the successful candidate is identified, the People department will send a Job Offer, specifying the start day, salary, working conditions, among other important details.

Deadline: Please submit your application by 25 /April/2025.

The contract will be financed by European Union’s HORIZON-HLTH-2021 program under grant agreement No 101057454.