Associate NGS Scientist

From the very beginning, we have been focusing on the science. We came together as a team of experts, committed to quality, driven by excellence, and dedicated to experimentation. Though we faced many challenges, we remained fearless in our research and rigorous in our thinking, pushing ourselves to work harder. However, what affected us the most was the enormous burden patients bear and the difficulties they face, which drove us to think about what’s next.

We believe it is time to accelerate and expand that transformation. At Legend Biotech, we are excited to bring clinical trials to patients in our pursuit of a cure. While we are focusing on CAR-T in multiple myeloma, we firmly believe the prospects of cellular therapy stretch beyond just one disease or indication. The spark of hope is lit. At Legend Biotech, we are using that hope to ignite the future of CAR-T cell therapy.

Job Description

Role Overview:

As an Associate NGS Scientist in the R&D team, you will contribute to the development of cutting-edge solutions for Next Generation Sequencing. This individual will be charged with implementing new next-generation sequencing assays as well as running existing validated assays and sequencers while following established policies and procedures in a professional manner. The successful candidate must be passionate about wet-lab driven experimentation and a team player.

Major Responsibilities:

• DNA and RNA extraction of biological samples.
• Library preparation for next generation sequencing.
• Develop and execute various QC methodologies to assess the quality of samples and run NGS sequencer.
• Maintain detailed laboratory notes on experiments, generate reports summarizing experimental results, and communicate them to project teams.
• Perform other lab experiments as planned and document all observations and findings.
• Participate with other R&D team members in troubleshooting and identifying new opportunities for optimization and applications.

Qualifications

Education: M.S or Ph.D preferred.

Experience:

• Proficiency with basic molecular biology techniques, DNA and RNA quantification technologies, PCR, and qPCR is required.
• 1+ year of direct hands-on experience with NGS library preparation and sequencing run setup is preferred.
• Illumina NGS workflow and platform experience.

Key Capabilities, Knowledge, and Skills:

• Able to multi-task effectively and be fully committed to project timelines.
• Strong organization and communication skills.
• Able to work in a fast-paced environment.
• Experience working in a regulated environment under a controlled design review process is preferred.